1 Stretch - induced fetal type II cell differentiation is mediated via ErbB 1 - ErbB 4 interactions
نویسندگان
چکیده
Background: Mechanical forces and ErbB receptors are critical for fetal lung development. Results: Deletion of ErbB1 or downregulation or ErbB4 prevented stretchinduced type II cell differentiation via ERK. Conclusion: Interactions between ErbB1 and ErbB4 are critical for stretch-induced type II cell differentiation. Significance: Learning how mechanical signal regulate fetal lung development is critical to develop strategies to accelerate lung maturation.
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